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From Nema Wiki
The Many Uses Of Peptides
Peptides are short polymers of amino acid monomers linked by peptide bonds. They're distinguished from proteins on the basis of size, typically containing less than 50 monomer units. A peptide is formed by joining several amino acids. When the quantity of proteins is less than about 50 these molecules are named peptides while larger sequences are known as proteins. The proteins are coupled by a peptide bond, a unique linkage where the nitrogen atom of one protein binds towards the carboxyl carbon atom of another.
Peptides can be found in every living cell and possess a variety of biochemical activities. They appear as enzymes, hormones, antibiotics, receptors, etc. peptide synthesis is done by coupling the carboxyl group or C-terminus of one amino acid to the amino group or N-terminus of another.
Peptides play a crucial role in fundamental physiological and biochemical functions of life. For decades now, peptide research has been growing as a field in science. They've recently received prominence in molecular biology for many reasons. The first is they allow the creation of antibodies in animals without the need to purify the protein of interest. This involves synthesizing antigenic peptides of parts of the protein of interest; they are then used to make antibodies in a rabbit or mouse from the protein. Another reasons curiosity about peptides has grown recently is that they have grown to be instrumental in mass spectrometry, allowing the identification of proteins of interest according to peptide masses and sequence; in this case they are most often generated by in-gel digestion after electrophoretic separation from the proteins.
Peptides have recently been utilized in the study of protein structure and function. For example, synthetic peptides can be used as probes to determine where protein-peptide interactions occur. Inhibitory will also be utilized in clinical research to look at the results of they around the inhibition of cancer proteins and other diseases.
As interest in peptides has grown, and so do techniques for manufacturing it and studying new applications for this. For example, the library is really a newly developed technique for protein related study. A library includes a large number of they that have a systematic mixture of amino acids; it possesses a powerful tool for drug design, protein-protein interactions, and other biochemical as well as pharmaceutical applications.
The interest in peptides will probably continue into the future. The amount of peptides entering clinical trials will probably grow, and the utilization of peptides conjugated to carbohydrates, antibodies and other proteins is likely to be frequent. Peptides will not only be used as the active component of recent drugs, but as "addictions" with other pharmaceutical agents. Additionally, the range of medical indications that peptides address will grow. Peptide-based substances will continue to locate commercial use. Probably peptides will discover increased usage to treat obesity, metabolic syndromes and Type 2 diabetes. Peptides will also be used to address currently symptoms and ailments that cannot be given drugs.
